Lab news and updates:
August 19, 2020 - It is with a heavy heart that the McKinnie lab shuts down and evacuates Santa Cruz due to the nearby CZU lightning complex wildfires. We thoroughly appreciate the heroic efforts of all the firefighters and first responders that are keeping UCSC and Santa Cruz safe from danger. Stay safe and healthy everyone!
June 30, 2020 - A comprehensive and collaborative Natural Product Reports review between the McKinnie, George (University of Adelaide) and Moore (UCSD) labs summarizes the isolation, structure elucidation, biological activity, biosynthesis, and chemical and enzymatic syntheses of an entire family of meroterpenoids! Find it here.
June 29, 2020 - Small peptide, big activity! A cryptic tripeptide in yellow scorpion toxin is shown to activate various beneficial cardiovascular signalling pathways in a recent Journal of Proteome Research article! Congratulations to the Pimenta and Verano-Braga labs and thanks for including our contribution from Shaun's PhD work! Find the article here.
June 16, 2020 - The McKinnie lab opens up again in accordance with all COVID-19 restrictions and guidelines.
June 2, 2020 - All about Nocardia! A collaborative paper with the Zeimert and Kaysser labs (University of Tubingen) and Moore lab (UCSD) that connects genomics to metabolomics in this pathogenic actinobacterial genus appears in mSystems! Find it here.
June 1, 2020 - The UCSC Committee on Research generously approved the McKinnie lab's Faculty Research Grant! Time to buy some HILIC columns!
May 26, 2020 - Old fold, new tricks! Our paper on the X-ray crystal structure of DabA, the N-prenyltransferase involved in domoic acid biosynthesis that possesses a terpene cyclase-like fold, appears in PNAS! Find it here.
Mar. 20, 2020 - A collaborative paper describing the nonlinear biosynthesis of alpiniamide from an unusual NRPS-PKS system appears in ACS Chemical Biology! Find it here.
Mar. 16, 2020 - Unfortunately due to COVID-19, the McKinnie lab will be working from home for the foreseeable future. Our work is not immediately essential to society right now, but staying safe and healthy definitely is.
Mar. 16, 2020 - The McKinnie lab is thrilled to welcome Jackson Baumgartner and Austin Hopiavuori as its inaugural PhD students! Honored to have the opportunity to mentor, collaborate, and make exciting new discoveries with them over the next few years!
Feb. 6, 2020 - McKinnie lab is fully cleared by EH&S to start work!
Jan. 27, 2020 - Welcome CB3 rotation students Jackson Baumgartner and Austin Hopiavuori for the next seven weeks!
Jan. 15, 2020 - Goodbye anatoxin-a(s) and hello guanitoxin! Our new perspective article explaining why this potent cyanobacterial neurotoxin needs a new name appears in Harmful Algae! Find it here.
Jan. 6, 2020 - A fun interdisciplinary study about antibiotics produced by cavity-causing Streptococcus bacteria is out in ACS Infectious Diseases! Find it here.
Jan. 1, 2020 - The McKinnie lab is beyond honored to receive a 2020 Thieme Chemistry Journals Award as selected by the editorial boards of Synthesis, Synlett and Synfacts! This award is presented to early-stage independent career investigators as a 'sign of recognition and career encouragement.' The full list of all awardees can be found here.
Dec. 10, 2019 - The UCSC Committee on Research generously approved the McKinnie lab's New Faculty Research Grant! Time to buy some bacterial strains!
Nov. 15, 2019 - Shaun gives an ACCESS program-sponsored seminar on his postdoc work at Cabrillo College (Aptos, CA)!
Nov. 7, 2019 - First McKinnie lab group meeting!
Sept. & Oct. 2019 - Welcome to five talented undergraduate students: Elise, Ethan, Griffin, Josh, and Mano! Excited to get the lab set up and do some great science with this team!
Sept. 16, 2019 - A collaborative paper between the Qian (Hong Kong University of Science and Technology), Zhang (UC Berkeley), and Moore (UCSD) labs describing a novel bioactive colibactin derivative that causes copper-dependent double stranded DNA breaks is out in Nature Chemistry! Find it here.
Sept. 1, 2019 - The McKinnie lab at UC Santa Cruz is founded!!